Nisreen Waleed Mustafa؛ Zaid Nabeel Elia؛ Sivan Jameel Toma
پوخته
Diabetes mellitus is one of public health problem in world. Type 2 diabetes millitus (T2DM) which resistance cell to insulin. more inflammation occur in Patients with T2DM because of ...
زیاتر بخوێنەوە
Diabetes mellitus is one of public health problem in world. Type 2 diabetes millitus (T2DM) which resistance cell to insulin. more inflammation occur in Patients with T2DM because of elevation of inflammatory marker like C3, C4 & hsCRP. This study was aimed to detect the level of acute phase reactant proteins (C3 , C4 and hsCRP) in T2DM patients.
Blood samples were collected from 60 patients with T2DM and control group was included 30 healthy donors. C3, C4 & hsCRP levels were estimated for all samples. Samples were grouped according to complications of patients.
The results showed that there was a significant increase in C3 level for patients with T2DM (199.0 mg/dl) compared to control group (135.4 mg /dl) while C4 level for T2DM (27.25 mg/dl) showed no significant change compared to control group( 30.04mg/dl). C3 level of patients under heart disease (199.6 mg/dl ), patients under thyroid disease (230.4 mg/dl) and patients without any disease (188.1 mg/dl) recorded significant elevation compared with control group (135.4 mg /dl) but C4 level did not show any significant change for all groups. hsCRP level recorded significant increasing in all study groups as fallowing : in all included patients (2.506 mg/L), T2DM patients with heart disease (2.238 mg/L),T2DM patients with thyroid disease (2.433 mg/L) and T2DM patients without any disease (2.20mg/L),
The conclusion of this study was the inflammation process associated with T2DM where inflammatory markers (C3 and hsCRP) elevated.